Case Series Describes Critical Illness Linked to MERS-CoV
TUESDAY, Jan. 28, 2014 (HealthDay News) -- Patients with critical illness associated with Middle East respiratory syndrome coronavirus (MERS-CoV) present with acute severe hypoxemic respiratory failure and most have extrapulmonary manifestations, according to research published online Jan. 28 in the Annals of Internal Medicine.
Yaseen M. Arabi, M.D., from King Saud bin Abdulaziz University for Health Sciences in Riyadh, Saudi Arabia, and colleagues describe critical illness associated with MERS-CoV in a cases series of 12 patients with confirmed or probable infection.
The researchers note that 114 patients were tested for suspected MERS-CoV between December 2012 and August 2013, of whom 11 intensive care unit patients met the definition of confirmed or probable cases. A health care-associated cluster was identified that included three of these patients and three health care workers, one of whom became critically ill and was the 12th patient in the MERS-CoV series. Among the patients, the median Acute Physiology and Chronic Health Evaluation II score was 28. All patients presented with acute severe hypoxemic respiratory failure and had underlying comorbid conditions. Ninety-two percent of the patients had extrapulmonary manifestations. Forty-two percent were alive at day 90. Only 1 percent of the 520 exposed health care workers were positive.
"Community-acquired and health care-associated MERS-CoV infection occurs in patients with chronic comorbid conditions," the authors write. "The health care-associated cluster suggests that human-to-human transmission does occur with unprotected exposure."
Full Text Editorial (subscription or payment may be requiredRelated Articles
Search Allergy Articles
What Is Chronic Sinusitis, and How Is it Treated?
Watchdog Group Says U.S. Food Recalls Rose Again Last Year
Sun Plus Certain Foods, Meds Can Bring on 'Margarita Rashes'
FDA Wants More Data on First Needle-Free Antidote for Severe Allergic Reactions
COVID Does Not Spur Asthma in Kids, Study Finds
Vitamin K May Kickstart Healthy Lungs
Nova Scotia Wildfires Sending Unhealthy 'Smoke Plume' to U.S. Northeast
Asthma Inhaler Switch in 2024 Could Leave Some Patients Scrambling
Sore Throat? Try These 5 Home Remedies for Relief
Folks Often Hide Infectious Illness at Work, Socializing
Texan Has Contracted H5N1 Bird Flu; CDC Calls Threat to Public 'Low'
Most U.S. Parents Plan to Vaccinate Kids Against Flu, RSV: Survey
Just 23% of U.S. Adults 'Definitely' Plan to Get New COVID Shot